Both passive lipoidal diffusion and carrier-mediated uptake are important transport mechanisms in drug disposition

• In: MODERATED DEBATE: CARRIER MEDIATED TRANSPORT THROUGH MEMBRANES: THE EXCEPTION OR THE RULE? on Monday, 14 April 2014, 16:00-17:30
• At: PSWC, Melbourne (Australia) (2014)
• Type: Presentation
• By: AVDEEF, Alex (In-ADME Research, New york city, United States of America)
• Abstract:

  The disposition of pharmaceuticals in the various organs of the body depends on the movement of drugs across cellular membranes. Recently, Kell and coworkers^1-5 put forward a controversial hypothesis that carrier-mediated transport accounts for all the cellular uptake of pharmaceuticals, and that passive lipoidal diffusion of drugs across..

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