A traditional herbal medicine sho-saiko-to affects expression and functional activities of pept1 and mrp2 in caco-2 cells

• In: Hospital Pharmacy Section - Poster session
• At: Cairo (Egypt) (2005)
• Type: Poster
• Poster code: HPS-P-040
• By: NAORA (Shimane University Hospital, Department of Pharmacy, Izumo, Japan)
• Co-author(s): Yamamoto (Shimane University Hospital, IZUMO, Japan)
  Nishimura (Shimane University Hospital, IZUMO, Japan)
  Uemura (Shimane University Hospital, IZUMO, Japan)
  Iwamoto, Kikuo (Shimane University Hospital, IZUMO, Japan)
  
• Abstract:

  Aim: It has been known that many kinds of herbal medicines can cause pharmacokinetic interactions with synthetic drugs. We have already demonstrated that Sho-saiko-to (SST), a commonly prescribed herbal medicine, upregulates MDR1 leading to the increased activity of MDR1. The purpose of this study is to clarify the effects of SST on the other..

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