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Preparation and evaluation of solid dispersion for nitrendipine-aerosil systems using melt-mixing method
- In: Industrial Pharmacy Section - Poster Session
- At: Cairo (Egypt) (2005)
- Type: Poster
- Poster code: IPS-P-024
- By: WANG (-, Nagoya, Japan)
- Co-author(s): Cui (Shenyang Pharmaceutical Univ., SHENYANG, China)
Sunada (Meijo University, NAGOYA, Japan) - Abstract:
Introduction
Nitrendipine (NTD), a dihydropyridine calcium channel blocking agent, is used to treat a variety of cardiovascular disorders. Due to its low aqueous solubility (about 2µg/mL), leading to the poor absorption of nitrendipine after oral administration, we prepared solid dispersions of nitrendipine to improve its dissolution rate and.. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.
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Last update 23 September 2026