Pristimerin regulates lipid biogenesis and mtor pathway by activating ampk in colon cancer cells

• At: Glasgow (Scotland) (2018)
• Type: Poster
• Poster code: POS-NPR-022
• By: YOUSEF, Bashir (Faculty of Pharmacy, University of Khartoum, Department of Pharmacology)
• Co-author(s): Bashir Alsiddig Yousef
  Hozeifa Hassan
  Luyong Zhang
  Zhenzhou Jiang
  
• Abstract:

  Background

  Reprogramming of metabolic pathways and enhancements of lipid biogenesis are important features of colorectal cancer cells (CRC). AMP protein kinase (AMPK) is a metabolic sensor that modulates lipid biosynthetic enzymes and mTOR signaling pathway. Pristimerin, a naturally occurring triterpenoid was previously reported by us to exhibit

  ..

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