Biodegradable hydrogels of recombinant thrombomodulin promotes chronic wound healing

• At: Glasgow (Scotland) (2018)
• Type: Poster
• Poster code: POS-FDP-022
• By: TSAI, Jui-Chen (NCKU Research and Development Foundation, Institute of Clinical Pharmacy and Pharmaceutical Sciences)
• Co-author(s): Yun-Yan Hsu: Department of Biochemistry and Molecular Biology, National Cheng Kung University, Tainan, Taiwan, Province of China;Institute of Clinical Pharmacy and Pharmaceutical Sciences, National Cheng Kung University, Tainan, Taiwan, Province of China
  Kuan-Lin Liu: Institute of Clinical Pharmacy and Pharmaceutical Sciences, National Cheng Kung University, Tainan, Taiwan, Province of China
  Hsun-Hua Yeh: Institute of Clinical Pharmacy and Pharmaceutical Sciences, National Cheng Kung University, Tainan, Taiwan, Province of China
  Hong-Ru Lin: Department of Chemical and Materials Engineering, Southern Taiwan University of Science and Technology, Tainan, Taiwan, Province of China
  Hua-Lin Wu: Department of Biochemistry and Molecular Biology, National Cheng Kung University, Tainan, Taiwan, Province of China
  Jui-Chen Tsai
  
• Abstract:

  Background

  Thrombomodulin (TM) is a type-I transmembrane glycoprotein expressed on the surfaces of endothelial cells and epidermal keratinocytes. It is known to regulate blood coagulation, inflammation, and cell-cell adhesion.  A recombinant TM, which contains an epidermal growth factor - like domain and serine/threonine-riches domain, has been..

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