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Pharmacokinetical analysis of telithromycin in lung for safe therapy of respiratory infections
- In: Posters - miscellaneous
- At: Basel (Switzerland) (2008)
- Type: Poster
- Poster code: M-P-002
- By: MORIMOTO, Kazuhiro (Hokkaido Pharmaceutical University, Otaru, Japan)
- Co-author(s): Togami, Kouhei (Hokkaido Pharmaceutical University, OTARU, Japan)
Chono, Sumio (Hokkaido Pharmaceutical University, OTARU, Japan)
Saso, Yuko (Hokkaido Pharmaceutical University, OTARU, Japan)
Seki, Toshinobu (Hokkaido Pharmaceutical University, OTARU, Japan) - Abstract:
Purpose. Telithromycin (TEL), a ketolide antibiotic agent, has a wide antimicrobial spectrum against bacterial pathogens of respiratory infection and high distribution characteristics from blood to lung. For safe therapy of respiratory infections, the pharmacokinetics of TEL from blood to lung surface and alveolar macrophages (AMs) were examined.
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