Solid dispersions tadalafil-Soluplus® formed by high-energy ball milling.
Impact of process parameters.

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-C-043-Monday
• By: KRUPA, Anna (Jagiellonian University, Medical College, Faculty of Pharmacy, Department of Pharmaceutical Technology and Biopharmaceutics, Krakow, Poland)
• Co-author(s): Anna Krupa: Pharmaceutical Technology and Biopharmaceutics, Jagiellonian University Medical College Faculty of Pharmacy, Krakow, Poland
  Dorota Majda: Faculty of Chemistry, Jagiellonian University, Krakow, Poland
  Katarzyna Dziewic: Pharmaceutical Technology and Biopharmaceutics, Jagiellonian University Medical College Faculty of Pharmacy, Krakow, Poland
  Renata Jachowicz: Pharmaceutical Technology and Biopharmaceutics, Jagiellonian University Medical College Faculty of Pharmacy, Krakow, Poland
  
• Abstract:

  Backgrounds

  Tadalafil is a high melting point poorly soluble drug. Thus, the amorphisation methods, which can be carried out at room temperature, and are organic solvents-free need to be optimized with the aim to improve its solubility.

  Aims

  The aim of this study was to investigate the impact of high-energy ball milling process parameters: (i)

  ..

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