New molecules against colistin-resistant clinical Acinetobacter baumannii strains. Synthesis of a small library of piperazine thiourea derivatives and in vitro biological evaluation.

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-A-045-Monday
• By: VEGA-PéREZ, José M. (Universidad de Sevilla. Facultad de Farmacia, Dpto. Química Orgánica y Farmacéutica, Sevilla, Spain)
• Co-author(s): Sarah Mazzotta: Dpto. Química Orgánica y Farmacéutica, Universidad de Sevilla. Facultad de Farmacia, Sevilla, Spain
  Margarita Vega-Holm: Dpto. Química Orgánica y Farmacéutica, Universidad de Sevilla. Facultad de Farmacia, Sevilla, Spain
  Fernando Iglesias-Guerra: Dpto. Química Orgánica y Farmacéutica, Universidad de Sevilla. Facultad de Farmacia, Sevilla, Spain
  Javier Sánchez-Céspedes: IBIS. Hospital Virgen del Rocío, Universidad de Sevilla, Sevilla, Spain
  Jerónimo Pachón: IBIS. Hospital Virgen del Rocío, Universidad de Sevilla, Sevilla, Spain
  Mª Eugenia Pachón-Ibáñez: IBIS. Hospital Virgen del Rocío, Universidad de Sevilla, Sevilla, Spain
  José M. Vega-Pérez: Dpto. Química Orgánica y Farmacéutica, Universidad de Sevilla. Facultad de Farmacia, Sevilla, Spain
  
• Abstract:

  Backgrounds

  The development of active compounds against Acinetobacter baumannii is an important goal of research, due to the number of nosocomial infections it causes and to its multidrug antimicrobial resistance.

  
  

  Based on our previous work in the synthesis of small libraries of biologically active compounds, after a preliminary screening, a 

  
  ..

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