Metabolic stability studies of drugs and potential drug candidates supported by LC-MS-based analytical approach

• In: Poster presentation
• At: Buenos Aires (Argentina) (2016)
• Type: Poster
• Poster code: POS-DDD-001
• By: BąCZEK, Tomasz (Medical University of Gdańsk, Department of Pharmaceutical Chemistry, Gdańsk, Poland)
• Co-author(s): Tomasz Bączek:|Mariusz Belka:Department of Pharmaceutical Chemistry,Medical University of Gdansk,Gdansk,Poland|Szymon Ulenberg:Department of Pharmaceutical Chemistry,Medical University of Gdansk,Gdansk,Poland
  
• Abstract:

  Drug metabolism is a major determinant governing both pharmacokinetics and clinical response and a great deal of efforts is directed to assess key metabolic parameters in early stages of drug development. A large number of drug candidates have undesirable properties, including low metabolic stability that could result in poor bioavailability or

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