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Studies on design, synthesis and bioactivities of no-donating derivatives of puerarin
- In: SIG Natural Substances - Posters
- At: Beijing (China) (2007)
- Type: Poster
- Poster code: NS-P-025
- By: SHI, Wei-bing (China Pharmaceutical University, Nanjing, China)
- Co-author(s): ZHANG, Yi-hua (China Pharmaceutical University, NANJING, China)
LAI, Yi-sheng (China Pharmaceutical University, NANJING, China)
JI, Hui (China Pharmaceutical University, NANJING, China)
LI, Yong-qi (China Pharmaceutical University, NANJING, China) - Abstract:
OBJECTIVE To study synthesis and anti-hypertensive activity of NO-donating derivatives of puerarin and to search for novel anti- hypertensive agents with high activity and less side effects. METHOD The title compounds were synthesized by coupling of organic nitrate or furoxan with puerarin, and the inhibitory activity against KCl-induced..
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