Signalling pathway of tumor cell death induced by lidamycin

• In: SIG Pharmaceutical Biotechnology - Posters
• At: Beijing (China) (2007)
• Type: Poster
• Poster code: PB-P-013
• By: HE, Qiyang (Institute of Medicinal Biotechnology, Beijing, China)
• Co-author(s): Yang, ajing (Institute of Medicinal Biotechnology, BEIJING, China)
  Wang, Zhen (Institute of Medicinal Biotechnology, BEIJING, China)
  Li, Diandong (Institute of Medicinal Biotechnology, BEIJING, China)
  
• Abstract:

  OBJECTIVE Lidamycin (LDM), a kind of antitumor enediyne antibiotic, potently inhibit tumor growth and metastasis. Therefore, deciphering the signaling pathways of tumor cell death initiated by LDM is of critical importance for clarifying the unique potent action of it. METHODS chromatin condensation was observed by fluorescence microscope, the..

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