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Aqueous remote loading of protein therapeutics in plga microspheres
- In: DDA SUBMITTED ORALS on Wednesday, 16 April 2014, 16:30-18:00
- At: PSWC, Melbourne (Australia) (2014)
- Type: Presentation
- By: SCHWENDEMAN, Steven (University of Michigan, Pharmaceutical Sciences, Ann arbor, United States of America)
- Abstract:
I. Background: We have developed an organic solvent-free encapsulation method based on polymer healing akin to the remote loading of doxorubicin in DOXIL stealth liposomes in order to minimize protein instability and improve potential of protein-controlled release. II. Aims: We sought to use this method to encapsulate therapeutic proteins in
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