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Imaging drug disposition
- In: MINI SYMPOSIUM: MOLECULAR AND FUNCTIONAL IMAGING IN DRUG DEVELOPMENT AND EARLY CLINIC on Wednesday, 16 April 2014, 09:00-10:00
- At: PSWC, Melbourne (Australia) (2014)
- Type: Presentation
- By: UNADKAT, Jashvant (Univ. of Washington, Dept. of Pharmaceutics, Seattle, United States of America)
- Abstract:
Traditional pharmacokinetic studies in human volunteers or patients can describe the absorption, distribution, metabolism and excretion of drugs from the reference point of blood or plasma. But, often this reference point does not reflect the pharmacokinetics of drugs at the site of efficacy and toxicity of drugs. This is because the fraction of
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