The value of not over-engineering - simple biocompatible nanoconstructs overcome mgst-1 mediated resistance in breast cancer

• In: SYMPOSIUM: SAFETY OF NANOMEDICINES: REALITY CHECK? on Tuesday, 15 April 2014, 13:00-14:30
• At: PSWC, Melbourne (Australia) (2014)
• Type: Presentation
• By: NYSTRöM, Andreas (Karolinska Instututet, Institute of Enviromental Medicine, Stockholm, Sweden)
• Co-author(s): Zeng, Xianghui (Karolinska Instututet, Stockholm, Sweden)
  
• Abstract:

  Resistance to single or multiple chemotherapeutic drugs is a major complication in clinical oncology and is one of the most common treatment limitations in patients with reoccurring cancers. Nanoparticle (NP)-based drug delivery systems (DDS's) have been shown to overcome drug resistance in cancer cells mainly by avoiding the activation of efflux

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