Reversal of liver fibrosis in chronic murine schistosomiasis mansoni by safironil/praziquantel

• In: Posters H - Pharmacology
• At: PSWC, Melbourne (Australia) (2014)
• Type: Poster
• Poster code: PH-006
• By: ALHARBI, Naif (Kind saud University, Pharmacy, Riyadh, Saudi Arabia)
• Co-author(s): Bahashwan, Saleh (Taibah University College of Pharmacy, Madihnah, Saudi Arabia)
  
• Abstract:

  Backgroumd
  In schistosomiasis, healing of parasite egg induced liver granuloma can lead to periportal
  fibrosis, and bleeding esophageal varices. Fibrogenesis is a dynamic potentially
  reversible process mediated through immunological responses to parasite eggs
  trapped in the liver[3DOTS] Collagen synthesis (especially type I) is quantitatively..

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