Development of lc-ms-ms method for simultaneous determination of prostaglandin e1 (pge1) and prostaglandin e1 ethyl ester (pge1-ee) in dog plasma

• In: Industrial Pharmacy Section - Poster Session
• At: Salvadore (Brazil) (2006)
• Type: Poster
• Poster code: IPS-P-010
• By: YONG, Chul Soon (College of Pharmacy, Yeungnam University, Gyeongsan-si, South-Korea)
• Co-author(s): Choi, Han-Gon (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Kwak, Mi-Kyoung (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Rhee, Jong-Dal (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Yoo, Bong-Kyu (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Kim, Jung-Ae (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Lyoo, Won Seok (School of Textiles, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Balakrishnan, Prabagar (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Bhandari, Krishna Hari (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Newa, Madhuri (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  
• Abstract:

  Purpose: To develop and validate liquid chromatography-mass spectrometry-mass spectrometry (LC-MS-MS) method for the simultaneous determination of prostaglandin E1 (PGE1) and prostaglandin E1 ethyl ester (PGE1-EE) in the plasma of beagle dog. Methods: 9-Anthracenecarboxylic acid was used as an internal standard. The plasma samples were..

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