Development and evaluation of SPG membrane emulsification system for enhanced oral bioavailability of itraconazole

• In: SIG Posters
• At: Amsterdam (the Netherlands) (2012)
• Type: Poster
• Poster code: FDP-P-35
• By: YONG, Chul Soon (Yeungnam University, College of Pharmacy, Gyeongsangbuk-do, South-Korea)
• Co-author(s): Lee, D.W. (Yeungnam University, Gyeongsangbuk-do, South-Korea)
  Cho, H.J. (Yeungnam University, Gyeongsangbuk-do, South-Korea)
  Kim, J.H. (Yeungnam University, Gyeongsangbuk-do, South-Korea)
  Hiep, T.T. (Yeungnam University, Gyeongsangbuk-do, South-Korea)
  Poudel, B.K. (Yeungnam University, Gyeongsangbuk-do, South-Korea)
  Ramasamy, T.G. (Yeungnam University, Gyeongsangbuk-do, South-Korea)
  Yoo, B.K. (College of Pharmacy, Gachon University, South-Korea)
  Kim, J.O. (Yeungnam University, Gyeongsangbuk-do, South-Korea)
  Marasini, N. (Yeungnam University, Gyeongsangbuk-do, South-Korea)
  
• Abstract:

  
  
  
  
  
  Background:
  Itraconazole, a triazole antifungal drug has low aqueous solubility and bioavailability. Lots of studies have been done to increase solubility of drug with emulsification technique. The emulsion prepared by Shirasu-porous-glass (SPG) membrane can be mono-dispersed and uniform sized emulsion with narrow size distribution.
  Aims:
  The

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