Formulation and evaluation of mucoadhesive bi-layer buccal tablets of Labetalol hydrochloride using natural polymers

• In: Posters
• At: Amsterdam (the Netherlands) (2012)
• Type: Poster
• Poster code: IPS-P-21
• By: SHABARAYA, Ramakrishna (Srinivas College of Pharmacy, Pharmacutics, Mangalore, India)
• Co-author(s): Aiswarya, K. (Srinivas College of Pharmacy, Mangalore, India)
  Azharuddin, M. (Srinivas College of Pharmacy, Mangalore, India)
  Shripathy, D. (Srinivas College of Pharmacy, Mangalore, India)
  Kamath, K. (Srinivas College of Pharmacy, Mangalore, India)
  
• Abstract:

  
  
  Background
  
  : Labetalol hydrochloride is a lipophilic anti hypertensive drug having poor bioavailability(25%) and shorter biological half life (t
  _1/2
  -4-6hr) and undergo first pass metabolism during the treatment.
  
  Aim
  
  : In present study an attempt was made to develop and evaluate buccoadhesive tablets of Labetalol hydrochloride using natural polymers

  ..

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