Investigating the potential of multifunctional excipients for enhancing the buccal permeability of tenofovir (TNF)

• In: Dissolution/In Vitro Release Performance Testing Posters
• At: Hyderabad (India) (2011)
• Type: Poster
• Poster code: DIV-P-08
• By: GOVENDER, Thirumala (University of Kwazulu Natal, South Africa, Durban, South Africa)
• Co-author(s): Branham, M. (University of KwaZulu Natal, South Africa, Durban, South Africa)
  Rhambarose, S. (University of KwaZulu Natal, South Africa, Durban, South Africa)
  Ojewole, E. (University of KwaZulu Natal, South Africa, Durban, South Africa)
  Ebrahim, S. (University of KwaZulu Natal, Durban, South Africa)
  Gcumisa, N.C. (University of KwaZulu Natal, Durban, South Africa)
  Gobind, V.K. (University of KwaZulu Natal, South Africa, Durban, South Africa)
  Ismail, H. (University of KwaZulu Natal, Durban, South Africa)
  Mdlolo, N. (University of KwaZulu Natal, South Africa, Durban, South Africa)
  Singh, D. (University of KwaZulu Natal, South Africa, Durban, South Africa)
  Suleman, N. (University of KwaZulu Natal, South Africa, Durban, South Africa)
  
• Abstract:

  Background: Buccal drug permeation is limited by low membrane permeability. Permeation enhancers have been shown to overcome these limitations. Pharmaceutical excipients which have mucoadhesion and controlled-drug release properties could also act as enhancers and may increase the pool of multifunctional excipients for buccal delivery systems. The

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