NMS-003 - Design and optimisation of novel benzimidazole hybrid structures capable of simultaneous peroxisome proliferator activated receptor γ (PPARγ) and angiotensin receptor (ATR) modulation

• At: Copenhagen (Denmark) (2025)
• Type: Poster
• Poster code: NMS-003
• By: SHOEMAKE, Claire
• Co-author(s): Mr Matthias Borg (University of Malta, Msida, Malta)
  Dr Claire Shoemake (University of Malta, Msida, Malta)
  
• Abstract:

  Introduction
  Metabolic Syndrome (MetS) linked to increased risk of diabetes and cardiovascular disease, remains a challenge to manage even with currently used pharmacotherapeutic options. Clinical trials indicate that dual PPARγ/ATR modulators could represent enhanced treatment options. This study aimed to model such molecules in silico using..

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