Novel cyp3a, cyp2c9 and cyp1a isozyme inhibitors increase oral absorption of low bioavailable drug

• In: SIG Bioavailability/Bioequivalence Posters
• At: New Orleans (USA) (2004)
• Type: Poster
• Poster code: BB-P012
• By: HU, Yoa-Pu (National Defense Medical Center, Taipei, China Taiwan)
• Co-author(s): Hsiong (National Defense Medical Center, TAIPEI, China Taiwan)
  Pao (National Defense Medical Center, TAIPEI, China Taiwan)
  Kuo (National Defense Medical Center, TAIPEI, China Taiwan)
  Wang (National Defense Medical Center, TAIPEI, China Taiwan)
  
• Abstract:

  It is the expression and function of the CYP450 isozymes that governs the rate and extent of metabolism of the substrates for the CYP450 family. We have thoroughly searched and listed the most important components in the so-called Chinese herbal enhancers. From these components, flavonoids, terpenoids and essential oils etc., were tested

  ..

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