Characterization and evaluation of solid dispersions of valsartan prepared with gelatin and hpmc2910

• In: Industrial Pharmacy - Posters
• At: Basel (Switzerland) (2008)
• Type: Poster
• Poster code: IPS-P-025
• By: YONG, Chul Soon (College of Pharmacy, Yeungnam University, Gyeongsan-si, Gyeongsangbuk-do, South-Korea)
• Co-author(s): Li, Dong Xun (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
  Sung, Jun Ho (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
  Woo, Jong Soo (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
  Lee, Jong Suk (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
  Im, Jong Seub (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
  Rhee, Jong-Dal (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
  Hong, Myung-Ja (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
  Lee, Young-Im (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
  Choi, Han-Gon (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
  
• Abstract:

  Solid dispersions prepared with gelatin and HPMC2910 as a carrier were investigated for improving the dissolution and bioavailability of valsartan, a poorly water-soluble compound. The solid dispersions with various ratios of gelatin to HPMC2910 were obtained by spray drying method. They were characterized using differential scanning calorimetry..

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