Effects of samryungbaekchulsan on the pharmacokinetics of an oral anticancer drug ts-1 in rats

• In: Poster presentation
• At: Seoul (South Korea) (2017)
• Type: Poster
• Poster code: POS-PAA-016
• By: SHIN, Beom Soo (Catholic University of Daegu, College of Pharmacy, Gyeongsan-si, Korea, Republic Of)
• Co-author(s): Tae Hwan Kim: Center for Pharmacometrics and Systems Pharmacology, University of Florida, Orlando, United States
  Min Gi Kim: School of Pharmacy, Sungkyunkwan University, Suwon, Korea, Republic Of
  Sungwook Park: School of Pharmacy, Sungkyunkwan University, Suwon, Korea, Republic Of
  Seok Won Jeong: College of Pharmacy, Catholic University of Daegu, Gyeongsan-si, Korea, Republic Of
  Seung Eun Cheung: College of Pharmacy, Catholic University of Daegu, Gyeongsan-si, Korea, Republic Of
  Da Young Lee: College of Pharmacy, Catholic University of Daegu, Gyeongsan-si, Korea, Republic Of
  Soyoung Shin: College of Pharmacy, Wonkwang University, Iksan, Korea, Republic Of
  Beom Soo Shin: College of Pharmacy, Catholic University of Daegu, Gyeongsan-si, Korea, Republic Of
  
• Abstract:

  Background

  TS-1 is an oral fluoropyrimidine anticancer agent that contains tegafur, oteracil, and gimeracil. Tegafur is a prodrug of 5-fluorouracil (5-FU), and gimeracil is an inhibitor of 5-FU metabolism. Although Samryungbaekchulsan (SBS) is a traditional oriental medicine that has been used to treat gastrointestinal disorders, the use of SBS in..

The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress. Please login