Pharmacokinetics of doxorubicin encapsulated long circulating lipid nanospheres

• In: Industrial Pharmacy Section Posters
• At: New Orleans (USA) (2004)
• Type: Poster
• Poster code: IPS-P013
• By: VEERAREDDY, Prabhakar Reddy (Kakatiya University, Univ. College of Pharm Sci., Warangal, India)
• Co-author(s): Patlolla, Ram Reddy (Kakatiya University, WARANGAL, India)
  Jannapally (Kakatiya University, WARANGAL, India)
  Vobalaboina, Venkateswarlu (Kakatiya University, WARANGAL, India)
  
• Abstract:

  Doxorubicin lipid nanospheres (LND) and long circulating lipid nanospheres (PEG-LND) were prepared by ion pairing of doxorubicin hydrochloride with dicetyl phosphate at a molar ratio of 1:2. The pharmacokinetics of LND and PEG-LND were compared to the doxorubicin solution (Dox-S). The same dose of each formulation (7.5 mg/kg) of doxorubicin was..

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