Preparation of cefuroxime axetil nanoparticles by rapid expansion of supercritical fluid technology

• In: Miscellaneous - Posters
• At: Beijing (China) (2007)
• Type: Poster
• Poster code: M-P-042
• By: VARSHOSAZ, Jaleh (Isfahan University of Medical Sciences, Isfahan, Iran)
• Co-author(s): Hassanzadeh, Farshid (Isfahan University of Medical Sciences, ISFAHAN, Iran)
  Mahmoudzadeh, Mahmoud (Isfahan University of Medical Sciences, ISFAHAN, Iran)
  Sadeghi, Amir (Isfahan University of Medical Sciences, ISFAHAN, Iran)
  
• Abstract:

  Cefuroxime axetil (CFA) is commonly exists polymorphous of crystalline and amorphous forms, of which the latter exhibits a higher bioavailability. As a poorly water-soluble drug, CFA features a low solubility and dissolution rate in the gastrointestinal tract, which limits its effective absorption and bioavailability. According to Noyes-Whitney..

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