Phytocannabinoid ?9-tetrahydrocannabinvarin increase inhibitory neurotransmission in mice cerebellum

• In: SIG Natural Substances - Posters
• At: Beijing (China) (2007)
• Type: Poster
• Poster code: NS-P-095
• By: MA, Yu-ling (University of Reading, Reading, United Kingdom)
• Co-author(s): Dennis, I (University of Reading, READING, United Kingdom)
  Weston, S (University of Reading, READING, United Kingdom)
  Whalley, B (University of Reading, READING, United Kingdom)
  Stephens, G (University of Reading, READING, United Kingdom)
  
• Abstract:

  G-protein coupled cannabinoid CB1 receptors play a major role in presynaptic inhibition Within the cerebellum. In particular, CB1 is prominently expressed in inhibitory synapses between interneurones and Purkinje cells. We combine single and multi-electrode electrophysiological recording in acute brain slices with GTPγS binding assays in..

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