Use of Central Composite Design for Statistical Optimization of Nystatin-Loaded Solid Lipid Nanoparticles

• In: Poster presentation
• At: Buenos Aires (Argentina) (2016)
• Type: Poster
• Poster code: POS-FDP-012
• By: SILVA, André (Universidade Federal Do Rio Grande Do Norte, Laboratório de Sistemas Dispersos, Natal, Brazil)
• Co-author(s): Leny Nascimento:Laboratório de Sistemas Híbridos,Universidade Federal do Rio de Janeiro,Rio de Janeiro,Brazil|Nadilaine Barros:Laboratório de Sistemas Híbridos,Universidade Federal do Rio de Janeiro,Rio de Janeiro,Brazil|Talita Castiglione:Laboratório de Sistemas Híbridos,Universidade Federal do Rio de Janeiro,Rio de Janeiro,Brazil|Francisco Alexandrino-Junior:Laboratório de Sistemas Híbridos,Universidade Federal do Rio de Janeiro,Rio de Janeiro,Brazil;Laboratório de Sistemas Dispersos,Universidade Federal do Rio Grande do Norte,Natal,Brazil|André Leandro Silva:|Kattya Silva:Laboratório de Sistemas Híbridos,Universidade Federal do Rio de Janeiro,Rio de Janeiro,Brazil
  
• Abstract:

  Compared with others colloidal systems, solid lipid nanoparticles (SLN) offer combined advantages: low cost excipients, drug controlled release, low toxicity because of the absence of solvents in the production process and ease scaling-up. Nevertheless, some important characteristics to pharmaceutical purpose, as particle size, are significantly..

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