The anti-influenza virus activities of a long chain ester derivative-1c of zanamivir in vitro and in vivo

• In: SIG Individualised Medicine - Posters
• At: Beijing (China) (2007)
• Type: Poster
• Poster code: IM-P-005
• By: TAO, Peizhen (Institute of Medicinal Biotechnology, Beijing, China)
• Co-author(s): Wang, bo (Institute of Medicinal Biotechnology, BEIJING, China)
  Liu, zongying (Institute of Medicinal Biotechnology, BEIJING, China)
  Li, zhuorong (Institute of Medicinal Biotechnology, BEIJING, China)
  
• Abstract:

  Objective The present study aimed to test the anti-influenza virus activities of a zanamivir derivative 1c. Methods The cytotoxicities and antiviral activities of 1c in vitro on four influenza virus A strains and three influenza virus B strains were tested in MDCK cells. The antiviral activities of 1c in vivo were tested in the mice infected with ..

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