Preparation of curcumin solid lipid nanoparticles and evaluation of its pharmacokinetics in rats

• In: G37 - Manufacturing and good manufacturing practice IPS (part 1) on Wednesday, 5 September 2007, 9:00-11:45
• At: Beijing (China) (2007)
• Type: Presentations + Posters
• By: LI, Juan (China Pharmaceutical University, Nanjing, China)
• Co-author(s): Wang, Guang-ji (China Pharmaceutical University, Nanjing, China)
  Wei, Yun (China Pharmaceutical University, Nanjing, China)
  
• Abstract:

  OBJECTION To prepare curcumin solid lipid nanoparticles(CM-SLN) using emulsify-ultrasound method. The pharmacokinetics of CM-SLN, after intravenous (i.v.) administration to male Wistar rats were evaluated.METHODS The formulations of CM-SLN were optimized by uniform experimental design method. Particle size and charge measurements were made with

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