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Discovery of novel cd4 inhibitors as immunosuppressive agents
- In: SIG Pharmaceutical Biotechnology - Posters
- At: Beijing (China) (2007)
- Type: Poster
- Poster code: PB-P-014
- By: HE, Xinhua (Institute of Military Medical Sciences, Beijing, China)
- Co-author(s): Zheng, Zhibing (Institute of Military Medical Sciences, BEIJING, China)
Xiao, He (Institute of Military Medical Sciences, BEIJING, China)
Zhang, Han (PLA 301 Hospital, BEIJING, China) - Abstract:
Abstract â€'â€'To optimize the structure of TJU103, we firstly analyzed its pharmic core, and then applied classical drug design rules to modify TJU103 continuously to designed a molecular database which contained two kinds of compounds. The molecule databases were screened by using DOCK4.0 to select molecules for chemical synthesis. 51..
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Last update 2 July 2026