Statin-based bio-microemulsions l/h formulation

• In: Industrial Pharmacy Section - Poster Session
• At: Salvadore (Brazil) (2006)
• Type: Poster
• Poster code: IPS-P-042
• By: DOMINICI, Victor (UFRN, Natal, Brazil)
• Co-author(s): Damasceno, Bolívar (UFRN, NATAL, Brazil)
  Almeida, Diego (UFRN, NATAL, Brazil)
  Verissimo, Lourena (UFRN, NATAL, Brazil)
  Araújo, Ivonete (UFRN, NATAL, Brazil)
  Medeiros, Aldo (UFRN, NATAL, Brazil)
  Egito, E. Sócrates (UFRN, NATAL, Brazil)
  
• Abstract:

  Simvastatin (SIV) is a statin cholesterol-lowering agent used to treat hypercholesterolemia. However, pharmacological studies suggest clinical evidence of SIV as an anti-atherosclerotic drug. On the other hand, this molecule is practically insoluble in water and poorly absorbed by the gastro-intestinal tract. In addition, SIV induced muscle..

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