Dissolution enhancement of celecoxib solid dispersion using spray drying and precipitation with antisolvent

• In: Posters I - Regulatory Sciences
• At: PSWC, Melbourne (Australia) (2014)
• Type: Poster
• Poster code: PI-009
• By: HWANG, Sung-Joo (Yonsei Univ., College of pharmacy, Incheon, South-Korea)
• Co-author(s): Ahn, Junhyun (Yonsei Univ., Incheon, South-Korea)
  Sun, Bo-Kyung (Yonsei Univ., Incheon, South-Korea)
  Hyun, Sang-Min (Yonsei Univ., Incheon, South-Korea)
  Song, In-Ho (Yonsei Univ., Incheon, South-Korea)
  Kwon, Min-Jun (Yonsei Univ., Incheon, South-Korea)
  Kim, Taek Sun (Yonsei Univ., Incheon, South-Korea)
  
• Abstract:

  Background
  Celecoxib is a poorly water-soluble drug, and bioavailability is very low. In order to enhance the bioavailability of poorly water-soluble drugs, a number of pharmaceutical technologies are being developed to overcome difficulties. These include micronization and solid dispersions (SDs).
  Aims
  The purpose of this study is to enhance..

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