New drug targeting and monitoring of bendamustine treatment in patients with chronic lymphocytic leukemia (cll)

• In: Hospital Pharmacy Section Posters
• At: New Orleans (USA) (2004)
• Type: Poster
• Poster code: HPS-P001
• By: KOSTOVSKI, Aleksandar (Faculty of Pharmacy, Sofia, Pharmacology and Toxicology, Sofia, Bulgaria)
• Co-author(s): Konstantinov (Faculty of Pharmacy, Sofia, SOFIA, Bulgaria)
  Alaikov (University Hospital St. Anna, Bulgaria)
  Karaivanova (Faculty of Pharmacy, Sofia, SOFIA, Bulgaria)
  
• Abstract:

  Summary
  
  CLL is characterized by a progressive accumulation of functionally incompetent long-lived CD5+ B-lymphocytes which are monoclonal in origin. Bendamustine is a benzimidazole derivative with two alkylating groups. Fludarabine is a fluorinated adenine derivative belongs to the group of antimetabolites. Erucylphospho-N, N,..

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