CBS-005 - Elucidation of the mechanism of allergic sensitization enhanced by non-steroidal anti-inflammatory drugs in a rat model

• At: Copenhagen (Denmark) (2025)
• Type: Poster
• Poster code: CBS-005
• By: TAKIZAWA, Daigo (Department of Pharmaceutical Services, Hiroshima University Hospital, Japan)
• Co-author(s): Mr Daigo Takizawa (Department of Pharmaceutical Services, Hiroshima University Hospital, Hiroshima, Japan)
  Dr Tomoharu Yokooji (Department of Frontier Science for Pharmacotherapy, Graduate School of Biomedical and Health Sciences, Hiroshima, Japan)
  Ms Chie Uekawa (Department of Frontier Science for Pharmacotherapy, Graduate School of Biomedical and Health Sciences, Hiroshima, Japan)
  Dr Ryohei Ogino (Department of Frontier Science for Pharmacotherapy, Graduate School of Biomedical and Health Sciences, Hiroshima, Japan)
  Dr Takanori Taogoshi (Department of Pharmaceutical Services, Hiroshima University Hospital, Hiroshima, Japan)
  Prof Hiroaki Matsuo (Department of Pharmaceutical Services, Hiroshima University Hospital, Hiroshima, Japan)
  
• Abstract:

  Background : Allergic reactions to foods are often caused by allergen-specific immunoglobulin E (IgE) under T-helper type (Th) 2 cell-dominant conditions. We have previously reported that non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin and indomethacin (IND), non-selective cyclooxygenase (COX)-1 and COX-2 inhibitors, facilitate the..

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