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Multimorbidity, polypharmacy and regimen complexity: the example of people with cognitive and functional decline

  • In: SYMPOSIUM: PHARMACOEPIDEMIOLOGY: BRIDGING PHARMACEUTICAL SCIENCE AND PRACTICE on Monday, 14 April 2014, 10:30-12:00
  • At: PSWC, Melbourne (Australia) (2014)
  • Type: Presentation
  • By: BELL, Simon (Monash University, Centre for Medicine Use and Safety, Parkville, Australia)
  • Abstract:

    Polypharmacy and multimorbidity are common exclusion criteria in randomised controlled trials (RCTs). RCTs may be underpowered or not designed to assess a range of adverse events considered important to older people, including impaired cognition, hospitalisation and institutionalisation. Most RCTs have a drug-specific focus without considering an..

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