Physiological based PK modeling - applications to decision making in biopharmaceuticals

• In: S3 - Improving bioavailability/bioequivalence on Tuesday, 4 September 2007, 9:00-12:00
• At: Beijing (China) (2007)
• Type: Presentation
• By: AHR, Gertrud (Bayer HealthCare AG, Wuppertal, Germany)
• Co-author(s): Brendel, Erich (Bayer HealthCare AG, Wuppertal, Germany)
  Mueck, Wolfgang (Bayer HealthCare AG, Wuppertal, Germany)
  Willmann, Stefan (Bayer Technology Services, Leverkusen, Germany)
  Lippert, Joerg (Bayer Technology Services, Leverkusen, Germany)
  
• Abstract:

  Aim: Physiological based PK modeling (PB/PK)1,2 is available as commercial programs to support decision making in biopharmaceutical development. Application examples are presented how PB/PK may support scientists to compartmentalize their understanding and to divide the process from oral drug intake until drug absorption into the several steps

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