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Solid-lipid nanoparticles as a novel technology for delivering minocycline to the ischaemic brain
- In: D14 What’s new in industry and science? Part 1 on Monday, 3 September 2018, 16:30 -16:40
- At: Glasgow (Scotland) (2018)
- Type: Presentation
- By: WALKER, Roderick (Rhodes University, South Africa)
- Co-author(s): Janeeta Ranchhod: Faculty of Pharmacy, Rhodes University, Grahamstown, South Africa
Roderick Bryan Walker: Faculty of Pharmacy, Rhodes University, Grahamstown, South Africa - Abstract:
Background
Minocyline exhibits anti-inflammatory, anti-apoptotic and neuroprotective activity unrelated to its antibiotic properties making it a candidate for treating stroke [1]. Nanotechnology has yielded encouraging results for delivery of drugs to the CNS.
Methods
Design of Experiments (DoE) and Response Surface Methodology (RSM) was used
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