Preparation of novel polymeric microparticles for slow-release intrathecal delivery of analgesics

• In: SUBMITTED ORALS on Wednesday, 16 April 2014, 13:00-14:15
• At: PSWC, Melbourne (Australia) (2014)
• Type: Presentation
• By: HAN, Yaqin (University of Queensland, Centre for integrate preclinical drug development (CIPDD and School of Pharmacy, Brisbane, Australia)
• Co-author(s): Thurecht, Kristofer J. (University of Queensland, Brisbane, Australia)
  Whittaker, Andrew K. (University of Queensland, Brisbane, Australia)
  Smith, Maree T. (University of Queensland, Brisbane, Australia)
  
• Abstract:

  Biodegradable polymeric microspheres have been used extensively in sustained-release drug delivery formulations. Considerable previous research has focussed on encapsulation of hydrophilic drugs such as proteins and peptides, into a poly(lactic-co-glycolic acid) (PLGA) matrix using double-emulsion solvent evaporation methods. However, there is..

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