Quantitative analysis of estrogen derivative residue in poliomyelitis vaccine by high-performance liquid chromatography with fluorescence detection

• In: SIG Quality of Pharmaceuticals - Poster Session
• At: Cairo (Egypt) (2005)
• Type: Poster
• Poster code: QP-P-002
• By: TJAHJONO, Daryono Hadi (Institut Teknologi Bandung, Department of Pharmacy, Bandung, Indonesia)
• Co-author(s): Kartasasmita, Rahmana E (Institut Teknologi Bandung, BANDUNG, Indonesia)
  Kania, Rika (Institut Teknologi Bandung, BANDUNG, Indonesia)
  
• Abstract:

  A quantitative HPLC-fluorescence method for estrogen derivative residue in poliomyelitis vaccine was developed and validated. Sample pretreatment included ethyl acetate extraction and solid-phase extraction on a C18 column. LC separation was performed on a column of Zorbax SB C18 (150 mm × 4.6 mm id, 5 mm of particle size), a fluorescence..

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