Development and validation of an lc-ms/ms bioanalytical method for quantification of homocysteine (hcy) in samples of human serum

• In: Posters A - Analytical Sciences and Pharmaceutical Quality
• At: PSWC, Melbourne (Australia) (2014)
• Type: Poster
• Poster code: PA-008
• By: GHASSABIAN, Sussan (The University of Queensland, Centre for Integrated Preclinical Drug Development, Brisbane, Australia)
• Co-author(s): Ahmad Rethwan, Nur (The University of Queensland, Brisbane, Australia)
  Griffiths, Lyn (Queensland University of Technology, Brisbane, Australia)
  Smith, Maree (The University of Queensland, Brisbane, Australia)
  
• Abstract:

  Background. Recent research¹ implicates elevated serum levels of homocysteine (HCY) in the pathobiology of migraine. Hence, the aim of this study was to develop and validate an LC-MS/MS bioanalytical method for quantification of HCY in serum samples from patients with migraine.
  Methods. To samples of human serum (20 µl) were added aliquots of..

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