Cytotoxic activity of novel 1,3-thiazolyl compounds
- In: Posters C - Drug Design and Discovery
- At: PSWC, Melbourne (Australia) (2014)
- Type: Poster
- Poster code: PC-027
- By: BEZERRA, Daniel (Funda, Centro de Pesquisas Gon, Salvador, Brazil)
- Co-author(s): Moreira, Diogo (Funda, Salvador, Brazil)
Bomfim, Larissa (Funda, Salvador, Brazil)
Rocha, Suellen (Funda, Salvador, Brazil)
Leite, Ana (Universidade Federal de Pernambuco, Recife, Brazil)
Soares, Milena (Funda, Salvador, Brazil)
Background information: The thiazolic nucleus is found in a number of anticancer natural products, specifically in the 2-amino-1,3-thiazolic cyclic peptides.
Aims: In view of this, we designed a congeneric series of 1,3-thiazolic compounds, where these compounds feature a hydrazone and benzodioxole fragments.
Methods: 1,3-thiazolyl compounds (1-17).. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.