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Cytotoxic activity of novel 1,3-thiazolyl compounds

  • In: Posters C - Drug Design and Discovery
  • At: PSWC, Melbourne (Australia) (2014)
  • Type: Poster
  • Poster code: PC-027
  • By: BEZERRA, Daniel (Funda, Centro de Pesquisas Gon, Salvador, Brazil)
  • Co-author(s): Moreira, Diogo (Funda, Salvador, Brazil)
    Bomfim, Larissa (Funda, Salvador, Brazil)
    Rocha, Suellen (Funda, Salvador, Brazil)
    Leite, Ana (Universidade Federal de Pernambuco, Recife, Brazil)
    Soares, Milena (Funda, Salvador, Brazil)
  • Abstract:

    Background information: The thiazolic nucleus is found in a number of anticancer natural products, specifically in the 2-amino-1,3-thiazolic cyclic peptides.
    Aims: In view of this, we designed a congeneric series of 1,3-thiazolic compounds, where these compounds feature a hydrazone and benzodioxole fragments.
    Methods: 1,3-thiazolyl compounds (1-17)..

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Last update 4 October 2019

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