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Ratiometric dosing of indole-3-carbinol (I3C) and 2-methoxyestradiol (2ME) in cancer chemotherapy: a friend or a foe?

  • At: 2012 FIP Congress in Amsterdam (the Netherlands)
  • Type: Poster
  • By: AZAB, Samar (Ain Shams University, Faculty of Pharmacy, Pharmacology Department, Cairo, Egypt)
  • Co-author(s): Kratz, F. (Division of Macromolecular Prodrugs, Tumor Biology Center, Freiburg, Germany)
  • Abstract:

    BackgroundThe modulation of cellular signal transduction pathways by naturally occurring phytochemicals and hormones has recently been extended to elucidate the molecular basis of cancer chemotherapy. However, their use as chemosensitizers in breast cancer cells and modulating drug resistance is not fully elucidated.AimsThe fact that some drug


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Last update 4 October 2019

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