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Ratiometric dosing of indole-3-carbinol (I3C) and 2-methoxyestradiol (2ME) in cancer chemotherapy: a friend or a foe?

  • In: SIG Posters
  • At: Amsterdam (the Netherlands) (2012)
  • Type: Poster
  • Poster code: TRI-01
  • By: AZAB, Samar (Ain Shams University, Faculty of Pharmacy, Pharmacology Department, Cairo, Egypt)
  • Co-author(s): Kratz, F. (Division of Macromolecular Prodrugs, Tumor Biology Center, Freiburg, Germany)
  • Abstract:

    BackgroundThe modulation of cellular signal transduction pathways by naturally occurring phytochemicals and hormones has recently been extended to elucidate the molecular basis of cancer chemotherapy. However, their use as chemosensitizers in breast cancer cells and modulating drug resistance is not fully elucidated.AimsThe fact that some drug


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Last update 28 September 2023

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