Pharmacokinetic study of temoporfin-loaded invasomes after their in vivo topical application onto mice bearing subcutaneously implanted ht29 tumour

• At: Seville (Spain) (2022)
• Type: Poster
• Poster code: IPS-004
• By: DRAGICEVIC, Nina (Department of Pharmacy, Singidunum University, Serbia)
• Co-author(s): Prof Nina Dragicevic, Head Of The Department Of Pharmacy (Department of Pharmacy, Singidunum University, Belgrade, Serbia)
  Mag.pharm. Katarina Milosevic-Kostadinovic, Apoteka "Medicor" Dobrota (Apoteka "Medicor", Kotor, Montenegro)
  Prof. Alfred Fahr, Department of Pharmaceutical Technology (Department of Pharmaceutical Technology, Friedrich Schiller University Jena, Jena, Germany)
  
• Abstract:

  Background: Temoporfin (mTHPC) has a great potential for the topical photodynamic therapy. However, it presents a highly hydrophobic second generation photosensitizer with low percutaneous penetration. In order to use mTHPC for dermal/transdermal delivery it is necessary to employ some of the penetration enhancement methods.
  Aim: The goal was to..

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