Pharmacokinetic study of temoporfin-loaded invasomes after their in vivo topical application onto mice bearing subcutaneously implanted ht29 tumour
- At: Seville (Spain) (2022)
- Type: Poster
- Poster code: IPS-004
- By: DRAGICEVIC, Nina (Department of Pharmacy, Singidunum University, Serbia)
- Co-author(s): Prof Nina Dragicevic, Head Of The Department Of Pharmacy (Department of Pharmacy, Singidunum University, Belgrade, Serbia)
Mag.pharm. Katarina Milosevic-Kostadinovic, Apoteka "Medicor" Dobrota (Apoteka "Medicor", Kotor, Montenegro)
Prof. Alfred Fahr, Department of Pharmaceutical Technology (Department of Pharmaceutical Technology, Friedrich Schiller University Jena, Jena, Germany)
Background: Temoporfin (mTHPC) has a great potential for the topical photodynamic therapy. However, it presents a highly hydrophobic second generation photosensitizer with low percutaneous penetration. In order to use mTHPC for dermal/transdermal delivery it is necessary to employ some of the penetration enhancement methods.
Aim: The goal was to.. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.