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Inhibition of t cell proliferation by dictyostelium differentiation-inducing factors-1
- At: 2018 FIP Congress in Glasgow (Scotland)
- Type: Poster
- By: ZHOU, Jian-Rong (Sojo University)
- Co-author(s): Jian-Rong Zhou
BackgroundT cell play a central role in adaptive immune response. Differentiation-inducing factor-1 (DIF-1), a chlorinated alkylphenone, was found in the cellular slime mold Dictyostelium discoideum. DIF derivatives were found to promote mitogen-activated IL-2 production via AP-1 in Jurkat cells, while the effect on primary T cell is not yet.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.
Last update 13 May 2019