Synthesis and in vitro cytotoxic activities of some novel steroidal semicarbazones
- At: 2017 FIP Congress in Seoul (South Korea)
- Type: Poster
- By: CAKAR, Uros (Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia)
- Co-author(s): Uros Cakar: Department of Bromatology, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia
Marijana Zivkovic: Department of Chemistry, Institute for Chemistry, Technology and Metallurgy, Belgrade, Serbia
Ivana Matic: Institute of Oncology and Radiology of Serbia, Belgrade, Serbia
Dusan Sladic: Faculty of Chemistry, University of Belgrade, Belgrade, Serbia
Natalija Krstic: Institute of Oncology and Radiology of Serbia, Belgrade, Serbia
Steroids and their derivatives play important roles in human body and can serve as scaffolds for new drugs. Starting with four different steroidal diketones (1a-d), synthesis of eight novel semicarbazones (SCs) (2a-d and 3a-d) was done.
This work presents evaluation of in vitro cytotoxicity of obtained compounds against HeLa.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.