Synthesis and in vitro cytotoxic activities of some novel steroidal semicarbazones

• In: Poster presentation
• At: Seoul (South Korea) (2017)
• Type: Poster
• Poster code: POS-DDD-002
• By: CAKAR, Uros (Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia)
• Co-author(s): Uros Cakar: Department of Bromatology, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia
  Marijana Zivkovic: Department of Chemistry, Institute for Chemistry, Technology and Metallurgy, Belgrade, Serbia
  Ivana Matic: Institute of Oncology and Radiology of Serbia, Belgrade, Serbia
  Dusan Sladic: Faculty of Chemistry, University of Belgrade, Belgrade, Serbia
  Natalija Krstic: Institute of Oncology and Radiology of Serbia, Belgrade, Serbia
  
• Abstract:

  Background

  Steroids and their derivatives play important roles in human body and can serve as scaffolds for new drugs. Starting with four different steroidal diketones (1a-d), synthesis of eight novel semicarbazones (SCs) (2a-d and 3a-d) was done. 

  Purpose

  This work presents  evaluation of in vitro cytotoxicity of obtained compounds against HeLa

  ..

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