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Targeting colorectal neoplasia with rapamycin micelles in cpc;apc mouse model

  • At: 2014 FIP Congress in Bangkok (Thailand)
  • Type: Poster
  • By: KHONDEE, Supang (University of Phayao, School of Pharmaceutical Sciences, Pharmaceutical Sciences, Phayao, Thailand)
  • Co-author(s): Rabinsky, Emily F. (Department of Medicine, University of Michigan, Ann arbor, United States of America)
    Owens, Scott R. (Department of Pathology, University of Michigan, Ann arbor, United States of America)
    Joshi, Bishnu (Department of Medicine, University of Michigan, Ann arbor, United States of America)
    Qiu, Zhen (Department of Biomedical Engineering, Ann arbor, United States of America)
    Duan, Xiyu (Department of Biomedical Engineering, Ann arbor, United States of America)
    Zhao, Lili (Department of Statistics, University of Michigan, Ann arbor, United States of America)
    Wang, Thomas D. (Department of Medicine, University of Michigan, Ann arbor, United States of America)
  • Abstract:

    Annually more than million individuals are diagnosed with colorectal cancer (CRC) and with a death rate ~33%. Widely used non-specific chemotherapy worsens patient quality of life, despite its excellent efficacy. Thus, we formulated targeted rapamycin micelle to deliver lipophilic anticancer drug specifically and validated its therapeutic efficacy ..

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Last update 4 October 2019

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